Agents with the State Bureau of Investigation joined Durham police for a day-long search at the residence on Pear Tree Lane. Authorities began searching a second home on So Hi Drive near Ed Cook Road, which is down the road from the Pear Tree Lane home, Monday evening.
A City of Durham utilities crew helped with a search the sewer system in the neighborhood.
Pictures from Chopper 11 HD also showed police and agents searching a nearby wooded area.
Five- year-old Jadon Higganbothan and 28-year-old Antoinetta McKoy were last seen at the Pear Tree Lane home late last year.
McKoy and Higgenbothan reportedly lived in the house with Higgenbothan's mother Vania Sisk and several other women and children, who were members of a so-called cult called the "Black Hebrew Israelites," before the group suddenly moved to Colorado.
Search warrants previously obtained by ABC11 from Colorado indicate that investigators believe the boy was killed possibly by a man named Pete Moses Jr., who police believe is the leader of the group. Moses does not face any charges related to Higganbothan or McKoy.
A new Durham search warrant made public last week says blood, a spent bullet, and shell casings were found at the home in a previous search. The warrant also states there were signs of "overt cleaning in the areas of the residence where these crimes were stated to have occurred."
While Durham police continue to maintain their investigation is a missing person's case, the warrant says "according to numerous witnesses … Moses and Sisk were directly involved in the murder of a juvenile and an adult."