Around 10 a.m., police said a man and a woman were in a Saturn traveling on W. Chatham Street when the driver attempted to turn left onto Cary Parkway and collided with a Dodge.
"One of the cars was trying to make a left turn onto Cary Parkway from Chatham. Another car was traveling west on Cary Parkway. The two collided," said Lt. Jerry McCormick of the Cary Police Department.
The crash shut down the section of Cary Parkway between MacArthur Drive and W. Chatham Street until about 5 p.m.on Sunday.
Twenty-six-year-old Brian Cobb and 22-year-old Martikia Adams, both from Cary, were taken to WakeMed and later confirmed dead by police.
Cobb's family said he was on his way to work at a Cary Jiffy Lube.
The driver of the Dodge suffered only minor injuries and was not taken to the hospital.
Howard Kelly, a nearby resident, said the intersection is busy and that the accident was a "pretty bad one."
"This is one of the worst I've seen so far," said Kelly.
Neighbors said a stop sign at the intersection is often ignored.
No charges have been filed, and police said they are continuing their investigation with an accident report expected to be released on Tuesday.