Police said 20-year-old Xavier Freeman and 20-year-old Willie Dean Jr. were arrested Saturday while riding in a vehicle together in Lafayette.
Officers have charged them with murder for the death of 25-year-old Jeremy Lockett. He was shot and killed in June in front of a business at the intersection of Strickland Bridge Road and Fisher Road.
Another suspect, 30-year-old Charles Bush, was arrested a week.
Both suspects are being held, pending extradition back to Cumberland County, at the Lafayette Parish Correctional Center.