Police said the suspect(s) entered the home on Pebble Ridge Farms Road through an unlocked side garage door just after 1 a.m.
"We heard some rustling downstairs and we thought it was the kids and my husband noticed some flashing lights downstairs," said the homeowner, who didn't want to be identified.
Her husband jumped up, went to the top of the staircase, and engaged the intruder(s). After being confronted by the homeowner, the suspect(s) fled the scene on foot.
"We heard some more noise and he called out and then we heard running footsteps from the stairs or from the downstairs somewhere and right outside, out to our door and then our front door slammed," said the homeowner.
The couple told ABC11 that they aren't sure how many burglars there were or if they were armed.
No one was injured.
Police said only the one home was entered. However, neighboring homes were found with open fence gates.
The Cary Police Department reminds homeowners to take precautions like locking all doors and windows and leaving outside lights on overnight.
Anyone with information is on this incident should call police at (919) 469-4012 or Cary Crime Stoppers at (919) 226-CRIME.