Authorities said it happened in the 4800 block of U.S. Highway 421 around 4:30 p.m.
The accident involved a construction truck and a car.
According to the North Carolina Highway Patrol, the driver of the truck - 43-year-old Paul Thurman Ennis - crossed the center line and hit the car head on.
The two occupants of the car - 26-year-old JoAnna Christina Council, of Lillington, and 38-year-old Christian Lee Womack, of Raleigh - were both killed.
Ennis' passenger - 30-year-old Jonathan Dearl Mason, of Dunn - was treated and released from the hospital. Ennis remained hospitalized at WakeMed Tuesday.
Troopers said the investigation continues and charges are pending.