A check of race records showed dozens from the Triangle area were there. ABC11 spoke with family members who were calling cell phones and checking social media sites for updates.
Kazem Yahyapour of Raleigh - who spoke with ABC11 by phone - said he was just 100 yards from the finish line when he heard the explosion.
"It was crazy, there was a huge noise," he said. "Pretty soon we saw the people running, crying with cell phones yelling bomb, bomb, two bombs!"
The Associated Press spoke with Frank Deruyter - who's listed as a speech pathologist at Duke - right after the explosions.
"There are a lot of people down," said Deruyter.
Yahyapour said there was mass panic - and it was the last thing he expected at a running race.
"You worry about weather and cramps, you never worry about something like that happening," he said.
You can check the names of people registered in the race at the Boston Marathon website - go to: http://bostonmarathon.com/individual.html