The two-day festival will be held on June 14 and 15 at the Hollywood Bowl. It will be presented by the Los Angeles Philharmonic Association for the first time.
Singer Al Jarreau and bassist Stanley Clarke will celebrate the life of the late George Duke at the opening concert on Saturday. Duke, a frequent participant of the jazz festival, died of leukemia last year at age 67.
Saturday's lineup also includes singer Dianne Reeves, The Kenny Barron Trio with special guest Ravi Coltrane, and The Arturo Sandoval Big Band.
On Sunday, the performers include Dave Holland's Prism with Kevin Eubanks, Craig Taborn and Eric Harland; "American Idol" winner Fantasia Barrino; and the James Cotton Blues Band with guest saxophonist Big Jay McNeely.
Comedian George Lopez will host the Playboy festival for the second year in a row. He took over from long-time emcee Bill Cosby last year.
The Associated Press contributed to this report.