It happened just before 9 a.m. when police said a Two Men And A Truck moving van collided with a disabled Honda in the eastbound lanes.
The driver of the Honda, Lenae Mary Rebecca Dew, of Raleigh, died.
The Freightliner truck then crossed the median into the westbound lanes and hit two SUVs.
Three people in those vehicles were taken to the hospital. Two have serious injuries.
Police said the crash remains under investigation and no charges have been filed.
Two Men And A Truck issued a statement Monday afternoon.
"The local franchise is working both internally and with local authorities during the ongoing accident investigation. Words cannot convey our sympathy for all those impacted by the accident and our thoughts and prayers are with them," it said.
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