Rates start at $8 an hour or $66 a day. Gas and insurance is included.
"Duke is committed to environmentally friendly transportation alternatives, and Zipcar's service is in line with the university's goal to provide more sustainable options to students, faculty and staff," said Kemel W. Dawkins, vice president for campus services in a statement released to the media.
Zipcar started its Duke service Thursday with two hybrid Prius vehicles and two Toyota Matrix cars. About 120 colleges nationwide offer the service.