One motel employee was shot in the hip during the incident. He was taken to Duke University Hospital, but his condition is not known at this time.
The two suspects ran out of the business and got in a white Nissan Maxima, driven by a third man.
Authorities are currently searching for the suspects.
Anyone with information is asked to call CrimeStoppers at 683-1200. CrimeStoppers pays cash rewards for information leading to arrests in felony cases and callers never have to identify themselves.