One-hundred and fourteen of those cases were diagnosed over the Labor Day weekend.
"The professors here are very concerned especially when it comes to their own health," NC State student Jordan Hammond told Eyewitness News. "They're always telling us if you feel sick, go ahead and get out of the classroom. Go ahead and take a day off or however long it takes. Go see student health services."
Other area schools have reported flu cases as well.
NCCU has 10 flu-like cases so far this year. Duke and UNC wouldn't give a specific number but confirm having cases on campus.