Last year, 12 motorists were killed and 1,370 were injured.
The Patrol says it will be targeting speeders and aggressive drivers. Operation Slow Down began Monday, Nov. 15 and will end on Sunday, Nov. 28.
"I have instructed our Troopers to crackdown on speeders this holiday weekend; speed is the leading cause of fatal collisions on our highways," said Colonel Michael Gilchrist, Commander of the State Highway Patrol.
The Thanksgiving holiday weekend officially begins at 6:00 p.m. on Wednesday, Nov. 24 and ends at midnight, Sunday, Nov. 28.
Citizens can report highway problems to the Patrol by dialing *HP (*47) on their cellular phones. The toll free call goes directly to the nearest Highway Patrol communication center.