The home is located on South Mineral Springs Road. ABC11 Eyewitness News was on the scene as investigators carried two small children out of the home.
"The chemicals from cooking the meth were embedded in the furniture, in the floor, the carpet and it has to be decontaminated," Major Paul Martin, Durham Sheriff's Office, said.
Deputies made the discovery just before 7 p.m., after the sheriff's office says its narcotics unit received a tip about. Two children were in the house and had to be decontaminated before being taken to the hospital.
South Mineral Springs Road was blocked off for several hours as investigators combed through the home. The sheriff's office says it requested the SBI's assistance.
"The SBI will do some of the decontamination and then the county taxpayers have to pay for the house to be cleaned up," Martin said.
A woman who lives in the neighborhood says she saw authorities in action.
"Everybody had on the white suits, getting sprayed under that black thing right there and they was just spraying everybody down," the woman explained.
She says her neighbors mostly kept to themselves, although she noticed a lot of traffic. The woman, who asked not to be identified, is shaken by the news.
"We're staying beside a house that people are selling drugs out of, so it's kind of scary," she said.
Scary and unusual, according to investigators on the scene, who say they don't remember the last time they found a meth lab inside a home in the county.
"Our primary problems are with heroin, cocaine, marijuana, and various kinds of pills, but a meth lab is very rare, as far as we can determine in Durham County," Major Martin added.
Three adults were charged after the raid. Albert Carroll, 40, Crystal Brandi White, 38, and Daniel Johnston, 30, each face charges of manufacturing methamphetamine, possession of a precursor to methamphetamine, possession with intent to sell or distribute, possession of drug paraphernalia, maintaining a structure for the purpose of manufacturing methamphetamine, and two counts of child abuse.
Officials say one arrest is still pending in the case. Sheriff's investigators say they were able to make the bust because of a tip sent to them by e-mail. If you know of a crime happening, you can e-mail the Sheriff's department at email@example.com.