Officers were called about a shooting in the 1500 block of Gilmer Avenue just before midnight.
When they arrived, they found 27-year-old William Nolan Clark of Raleigh in front of a home. Authorities said he has been shot.
Clark was taken to Carilion Roanoke Memorial Hospital where he was pronounced dead.
No arrests have been made at this time.
Anyone with information regarding this or other crimes should call the Roanoke Police Department at (540)853-5959 or Crime Line at (540)344-8500.