It happened after 6 p.m. in the 1000 block of Walton Drive/Highway 242, just south of Benson.
The North Carolina Highway Patrol said a woman was driving along Walton Drive when she lost control and slammed into a tree.
A man riding in the vehicle died at the scene. The woman was taken to the hospital with serious injuries. Their names have not been released at this time.
Authorities said weather and speed may be to blame for the accident, but an investigation is still ongoing.
Neighbors who live near where the accident happened told ABC11 that this is the second accident to happen in that spot in the past two weeks.