Police say 25-year-old Roman Black is charged with murder, and 24-year-old Ciara Jeffries was charged as an accessory. Both were arrested last week.
On July 31, 35-year-old Kyvevon Gayles was shot at an apartment in the 900 block of Seventh Avenue. He died five days later.
Police have not released a motive in the shooting.
Black and Jeffries are awaiting extradition.