It happened around 3 p.m. Tuesday in the home in the 3000-block of Piney Grove-Wilbon Road.
Click here for a Google map of the area.
Images from Chopper 11 HD showed major damage inside the home and to its roof.
There's no word on any injuries.
Crews battle house fire in Fuquay-Varina
FUQUAY-VARINA, N.C.
