Murphy died Wednesday in New York of leukemia, according to his representative, Domenick Nati. Murphy was 57.
He was perhaps best-known for his appearances on "Chappelle's Show" on Comedy Central. He collaborated with writing his brother's starring films "Norbert" and "Vampire in Brooklyn." He voiced roles in animated TV series that include "The Boondocks" and "Black Jesus."
Murphy's feature films include "Our Family Wedding," ''King's Ransom" and "CB4."
He is credited with appearances to air later this year on the TV drama series "Power."
READ MORE: Comedians, celebrities mourn Charlie Murphy null