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The accident was reported at approximately 3:45 p.m.m Morrisville Police said.
The victim was pronounced dead at the scene.
"Amtrak Train 74 came into contact with a person who was trespassing on the tracks," Amtrak spokeswoman Kimberly Woods told ABC11. "Service has been temporarily suspended as local law enforcement investigate the incident."
There were 29 passengers aboard the train, Woods said. No other injuries were reported.
Traffic in the area was not affected.
Train 74 is the Piedmont, which travels daily between Raleigh and Charlotte.
Morrisville Police are investigating. Morrisville firefighters assisted at the scene.