"We are heartbroken to hear this sad news about Grant. He was an important part of our Discovery family and a really wonderful man," Discovery wrote in a statement on its website.
Imahara also hosted the Netflix show White Rabbit Project, which aired in 2016.
One of the first to pay tribute to Imahara was his Mythbusters co-star Adam Savage, who remembered him as a brilliant engineer and a generous and gentle person.
"Working with Grant was so much fun. I'll miss my friend," he wrote in a tweet on Monday evening.
I’m at a loss. No words. I’ve been part of two big families with Grant Imahara over the last 22 years. Grant was a truly brilliant engineer, artist and performer, but also just such a generous, easygoing, and gentle PERSON. Working with Grant was so much fun. I’ll miss my friend.— Adam Savage (@donttrythis) July 14, 2020
Before he began hosting shows, Imahara worked in special effects for nine years at George Lucas' Industrial Light and Magic.
Imahara was a native of Los Angeles and trained as an electrical engineer at the University of Southern California before becoming known as a robotics expert.
According to the Discovery website, he created a custom circuit for the Energizer Bunny and was behind the electronics installation and radio programming on the current generation of bunnies.