Stay on top of breaking news stories with the ABC11 News App
Two vehicles, a Honda Odyssey and a Honda CR-V were involved in the crash, which happened about 4 p.m. on High House Road near Bond Park.
Police said one vehicle was going east and the other was traveling westbound when the crash happened.
Cary officials told ABC11 that three adults and a 6-month-old baby were in the vehicles. Police said they are now listed as having non-life-threatening injuries.
Both vehicles sustained extensive damage.
The road reopened shortly after 6:30 p.m.