Officers received a shooting call around 5:30 p.m. in the 2500 block of South Roxboro Street.
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When they arrived, two men were found suffering from gunshot wounds. A spokesperson with Durham police said that one man suffered critical injuries and the other suffered non-life-threatening injuries.
Both men were transported to the hospital for treatment.
No names have yet to be released, as the investigation is ongoing. There was also no information released regarding a suspect.
Anyone with information is asked to call CrimeStoppers at (919) 683-1200.