Investigators said Tarvarest Hargrave, 43 of Durham, bought about 3 pounds of cocaine from Luz Ortega, 44, Jason Anderson, 40, and Christopher Lopes, 28.
Hargrave and Ortega were arrested on John Brantley Boulevard near the entrance to building that houses American Airlines cargo and the USO. The two other suspects were arrested a half mile away on Rental Car Drive.
They were all charged with trafficking in cocaine.
Police said they made the drug bust after responding to a report about a shooting in the area. The shooting turned out to be a false alarm, but officers discovered the drug deal happening and made the arrests.