It happened in the 1700 block of Palmer Street around 12:15 p.m.
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Officials say they received a shooting call and when they arrived at the scene, a man, who has not been identified, was found with an apparent gunshot wound.
He was pronounced dead at the scene.
No names or information regarding a suspect have been released, as the investigation is ongoing.
Anyone with information is asked to call Investigator I. Harton at (919) 560-4440, ext. 29332 or CrimeStoppers at (919) 683-1200.