Durham Police say the crash happened in the 1700 block of Cheek Road around 3 p.m. when a 2005 Ford Explorer driven by Ernest Briggs ran off the left side of the road, into a ditch and went airborne striking a parked car.
The Explorer then flipped, collided with a guidewire and came to a rest on its wheels.
Police said Briggs was partially ejected from his vehicle and was taken to the hospital where he later died.
Speed is a suspected factor in the crash, investigators said.