Troopers told ABC11 crews on scene that a pickup truck slammed into a vehicle after the car ran a stop sign on Clinton Road at Hillsboro Street.
Deputies said the driver of the car was killed; however, two passengers survived, including his alleged girlfriend and a 2-week-old baby.
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Three people in the pickup were transported to the hospital with non-life-threatening injuries.
Authorities believe alcohol may have been a factor in the crash.
The North Carolina State Highway Patrol is further investigating.