"We know we can win against good teams, and we showed it," Rams quarterback Skyler Locklear said.
Omarion Hampton accounted for all five first-half touchdowns for the Rams, who broke open a game that was evenly contested for much of the first half.
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After Hampton's second score, Garner answered with a 3-yard touchdown run by Derrick Alston and a two-point conversion to tie the score at 14-14.
Cleveland again took the lead when Locklear hit Hampton with a 79-yard touchdown pass but the Trojans responded with a 31-yard TD pass of their own when Daveon Dunn found Russell Sanders for the score.
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But again, it was Hampton, scoring again to put the Rams up for good.
"We had like a talk, with the team, and we were just like, it was a focus thing," Hampton said.
Cleveland earned its third consecutive victory against Garner.
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