Cates, a civil rights activist, was a Chapel Hill man who was killed on campus in 1970.
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The 22-year-old, who lived near campus, attended a party and was stabbed to death by members of a white supremacist biker gang outside the student union.
Three men were charged with first-degree murder, and acquitted by an all-white jury.
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On Monday, the university will host a dedication ceremony at 4 p.m. honoring Cates' life and welcoming the new memorial.
It will be at a popular gathering spot on campus, 'The Pit.'