Little Debbie's tweet on Wednesday included photos of four of their snacks: the Christmas Tree Cakes, Nutty Buddy, Oatmeal Creme Pies and Honey Buns with the caption "One Gotta Go Forever."
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"Bye, bye Honey Buns. I never did care for them," Twitter user @starsongsky wrote.
"Christmas Tree cakes," suggested someone else.
The four snacks are some of the company's classic ones.
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They have yet to reveal what they will be doing.
"We didn't say it would be easy. #OneGottaGo" Little Debbie tweeted Thursday.