Playboy magazine will feature its first-ever transgender playmate. French model Ines Rau will appear in the November issue.
A top executive at the magazine said the decision is in line with their mission to embrace changing attitudes about sex.
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The model described it as "a compliment like I've never had."
Playboy tweeted the announcement Wednesday saying, "Being a woman is just being a woman."
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On Thursday, Playboy tweeted, "Standing on the right side of history," along with a reaction from social media:
"To those who can't handle this, Hugh Hefner fought for the rights of ALL people. This is beautiful to see."