Durham Police Department said a vehicle hit a man at the intersection of Riddle Road and S. Briggs Avenue around 11:40 p.m.
Police are working to learn the make and model of the vehicle that struck the man. They are unsure if speed or impairment was a factor in the crash.
Officials have not released the identity of the victim at this time.
Anyone with information is asked to contact the Durham Police Department at (919) 560-4935 ext. 29448 or call CrimeStoppers at (919) 683-1200.