It happened just before 9 a.m. in the 1000 block of Long Branch Road.
According to investigators, when traveling west on Long Branch, a silver Ford Fusion crossed the center line and hit a Toyota Highlander.
This caused the Toyota to roll over several times and hit a Kia Optima head-on where the car's passenger flew out of the windshield.
The driver of the Ford died at the scene.
The driver and passenger of the Kia were taken to a hospital with serious injuries. The driver of the Toyota was also taken to a hospital with serious injuries.
No further information has been released at this time.