It happened around 1 a.m. near North Roxboro Street and West Club Boulevard.
When officers arrived, they found a man suffering from a gunshot wound. He was pronounced dead at the scene.
On Monday, DPD identified the victim as Devondra Mach, 18, of Durham.
A second man with a gunshot wound was found. He was taken to a hospital with what were described as non-life-threatening injuries.
This appears to be an isolated incident, the Durham Police Department said.
The case remains under active investigation.
Anyone with information about this incident is asked to contact Investigator J. Turner at (919) 560-4440 ext. 29532 or CrimeStoppers at (919) 683-1200 or online at www.durhamcrimestoppers.org. CrimeStoppers pays cash rewards of up to $2,000 for information leading to arrests in felony cases, and callers never have to identify themselves.