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Authorities said the girl's father David Joiner, 36, of Clinton, was going west in a 2004 Explorer near White Oak when his tire blew out.
He then lost control of the car which overturned several times on the road.
10-year-old killed, 4 people injured in I-40 crash near Garner
According to Joiner's pastor, he was driving his daughter Gloria and three other children, including his son, to a Christian youth conference in Charlotte.
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Gloria, who was sitting in the front seat, was killed during the impact.
The other four people involved were transported to a nearby hospital; two with serious injuries and two with minor injuries.
Gloria would have started 5th grade at New Life Christian Academy in the fall.
Joiner is listed as a teacher on the school's website.
A GoFundMe has been created for Gloria's funeral expenses and to help with medical expenses for those injured.