The home, which is located on Mangum Hollow Drive, caught fire in the early afternoon Monday.
The fire sparked in the basement of the home while a family with children was inside. The entire family was able to escape the house without injury. Fire investigators credit working smoke detectors for alerting the family and allowing them to get out of harm's way.
The first firefighter injured in the response was working for the Northern Wake Fire Department. He was part of a team hauling a hose down into the basement where the fire started; he fell while going down the stairs.
He was taken to Duke Medical Center to be evaluated. His injuries are not life-threatening.
The second injured firefighter was with the Wake Forest Fire Department. That firefighter reportedly overheated and needed to be taken to the hospital as a precaution.
The fire has since been extinguished. ABC11 is working to gather more information about the cause of the fire and the extent of any damage.