The company's debug program is seeking federal approval to release up to 32 million non-biting male mosquitoes in Florida and California.
The insects carry a naturally-occurring bacterium that prevents them from producing offspring with wild female mosquitoes.
Because only males are released, they don't bite or spread disease. That means the population of disease-carrying mosquitoes could shrink over time.
The Environmental Protection Agency is reviewing the permit request.
The proposal comes as health officials in California recently reported that a mosquito sample tested positive for West Nile virus.
There are no reports of human cases but officials are urging residents to take precautions.