The incident happened around 9:30 a.m. on Route 72 near Mermaid Drive in the Manahawkin community of Stafford Township.
According to Stafford Township Police, an ICE agent was attempting to take someone into custody when that person fled the scene in a vehicle, allegedly striking the ICE agent.
The agent fired his gun at the vehicle, reportedly striking it, police say. That person fled the scene, and it's not known if that person was injured.
The ICE agent was injured, police said, but it is not known how serious the agent's injuries are.
Photos posted online showed a masked agent sitting on the ground, leaning against a vehicle bumper, before being placed on a stretcher.
It is not yet clear why agents were trying to arrest the person in the vehicle or if that person was ever apprehended.
An email seeking comment from Immigration and Customs Enforcement was not immediately returned.
(The Associated Press contributed to this report.)