Kerry now plans to return to the United States on Sunday after X-rays at a Swiss hospital confirmed that he fractured his right femur.
He will receive further treatment in Boston.
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State Department spokeswoman John Kirby says Kerry will be treated by the same doctor who performed a prior hip surgery.
Kirby says Kerry is stable, never lost consciousness and that his injury is not life-threatening.
He says Kerry should make a full recovery and is in good spirits.
Ending the trip means Kerry is skipping meetings with Spanish leaders and a conference in Paris on fighting the Islamic State group.