Republicans
North Carolina Republican Party (NCGOP) released this statement:
"Roy Cooper has a 40-year record to defend where he's raised taxes, locked down schools, pardoned violent criminals, and failed in helping our fellow citizens recover from devastating hurricanes. North Carolinians have had enough of radicals like Roy Cooper, who make their living off the taxpayers while supporting policies that make life unaffordable for families. He will not be our next U.S. Senator."
National Republican Congressional Committee Chairman Richard Hudson issued the following statement:
"Roy Cooper spent decades dragging North Carolina left, and now he wants to do the same to America. Roy Cooper supports men playing in girls' sports and raising taxes on working families. Roy Cooper marched with protestors and then let them burn Raleigh. And Roy Cooper assured all of America that Joe Biden was perfectly capable of being President for four more years. Roy Cooper doesn't want to make America great again; he just wants to take America Left."
Democrats
Congresswoman Deborah Ross released the following statement:
"I have known Roy Cooper for more than three decades. He is a leader of uncommon integrity who has dedicated his life to fighting for the people of North Carolina. I proudly endorse him for U.S. Senate. Roy was our state's outstanding governor during difficult times, and he is absolutely the right person to serve as our next senator. He successfully expanded Medicaid after more than a decade of political gridlock - putting life-saving healthcare within reach for 600,000 people. He also oversaw a rapidly growing economy and coordinated an effective response to Hurricane Helene, which enabled our state to serve our people no matter their zip code. Roy will hold Donald Trump and his Republican allies accountable for their attacks on our state and its people. He will fight hard every day for more opportunity, better health care, and a brighter future for every North Carolinian. I look forward to doing everything I can to help elect Roy Cooper in November."
Senate Minority Leader Chuck Schumer and Democratic Senatorial Campaign Committee (DSCC) Chair Kirsten Gillibrand released the following statement:
"Governor Cooper is a proven leader who has dedicated his life to serving North Carolina. From expanding Medicaid for hundreds of thousands of North Carolinians to bringing good-paying jobs to the state and taking on scammers and big banks, Cooper has always been a champion for North Carolina families. Governor Cooper is a formidable candidate who will flip North Carolina's Senate seat, and his announcement is the latest indication that the Republicans' Senate majority is at risk in 2026."
Gov. Josh Stein, who served as attorney general under Cooper's governorship, said in a fundraising email to supporters that "Gov. Cooper has my confidence, my endorsement and my vote. ... I am proud to call Gov. Cooper a friend and grateful for the lifetome of service he's already given to North Carolina."