The crash happened at the Reedy Creek Overpass about 3:30 p.m.
Traffic was backed up all the way to Chapel Hill Road in Raleigh.
Multiple vehicles were involved in the crash. One car was off the road in a ditch.
Three lanes reopened around 4 p.m. All lanes reopened by 4:35 p.m.
There was no immediate word on any injuries.
Traffic is moving but drivers should avoid the area if possible.