It happened around 4:15 a.m. along the westbound lanes of I-40 near Aviation Parkway and Airport Boulevard.
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It is unclear what caused the SUV to overturn in the grassy shoulder, but two people inside the vehicle were able to get out before first responders arrived.
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They appeared to have minor injuries and were treated at the scene.
Authorities had to close the right lane to traffic as they worked to clear the scene.