The UNC Health System says they've seen nearly 200 cases just within the last week, pediatric beds are full and patients are facing long wait times.
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They say they've had to turn some people away and delay elective surgeries.
Duke Health is also seeing a high demand for pediatric beds. As of last week, they reported 241 positive RSV cases.
RSV symptoms include fever, coughing, wheezing, change or loss of appetite and fatigue.
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Earlier this month, ABC11 talked to medical professionals who predicted an increase in cases.
They want parents to have their kids wash their hands, use social distancing and wear a mask when possible.
Doctors say most cases are mild, but parents should be on alert for warning signs of a bigger problem.
WATCH | RSV cases concern parents, doctors nation wide.
Doctors concerned as RSV cases continue to spike nationwide