The budget airline will offer daily, non-stop service to seven cities starting on May 2.
In a tweet on Tuesday morning, the airport announced the partnership and flight routes.
Starting on May 2, Spirit will offer nonstop service to the following destinations:
According to RDU, the flights will either be on the 145-seat Airbus A319 or the 182-seat Airbus A320.
Spirit is the 10th carrier to serve RDU travelers.
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