"My love, my best friend, our hero, our coach is now our guardian angel I LOVE YOU Tony Leonard," his wife Christy posted to Facebook on Wednesday.
On Tuesday, she told loved ones that he would soon pass on.
"Our warrior is no longer responsive except for light blinks when we say I love you," she posted. "...Our warrior is almost ready. Please keep praying for a painless transition."
Leonard and Christy renewed their vows in an emotional ceremony in January.
Lenoard was diagnosed with cancer in 2012.
The cancer returned just after his five-year cancer-free anniversary and spread to his lymph nodes and three other organs in early 2018.
He had his organs removed to prevent the disease from spreading.
In February 2018, he received a wish off of his bucket list from the Fill Your Bucket List Foundation: attending the first matchup of the season between Duke and Carolina at the Dean Smith Center with his family.