DeBose will hit the red carpet this year as one of the presenters.
DeBose won the Best Supporting Actress Oscar last year for her breakout performance as Anita.
The honor came 60 years after Rita Moreno claimed the award in 1962 for the original film version of the Broadway musical.
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Sunday, she presented for the Best Supporting Actress which was won by Jamie Lee Curtis.
She also presented the Best Supporting Actor and got emotional while announcing the winner, Ke Huy Quan.
Jimmy Kimmel will host for the third time and his first time since 2018, the last Oscars to feature a solo host. The late-night host said he's just about ready for anything.
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You can see a full list of presenters and performers here.
See a full list of nominees ahead of the big show.