Police identified the man as 29-year-old Keith Antonio Watson, of Durham.
It happened in the 4200 block of Larchmont Road.
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Officers arrived about 5:15 p.m. to find a man dead and a woman injured.
The female victim was treated for her injuries and released from the hospital.
Her identity is not being released at this time.
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No charges have yet been filed. The shooting remains under investigation.
Anyone with information is asked to call Investigator T. Huelsman at (919) 560-4440, ext. 29341 or CrimeStoppers at (919) 683-1200. CrimeStoppers pays cash rewards for information leading to arrests in felony cases and callers never have to identify themselves.