It happened around 6 p.m. on Naples Place.
Two people were shot, 43-year-old Santiago Lopez Paz and a 17-year-old relative. They were standing outside when the shots rang out.
Lopez Paz was rushed to the hospital where he died. The teen sustained non-life-threatening injuries.
Two other people in the area said they were robbed at gunpoint just before the shooting.
The shooters were seen driving away from the area in a silver or gray Honda.
Durham Police Department has not made any arrests or identified the suspects.
Anyone with information that could help investigators is asked to call CrimeStoppers at 919-683-1200.