The crash happened at the Cornwallis Road overpass around 7:30 a.m.
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According to the North Carolina State Highway Patrol, a Hyundai Elantra was traveling eastbound on the highway when it hit a deer.
The car then went off the roadway and hit a guardrail, overturned and hit the bridge.
The 18-year-old driver was pronounced dead at the scene, according to The JoCo Report.
The State Highway Patrol said speed was also a factor.