Investigators had been working a case when a woman was shot and killed on Aug. 2 in the 300 block of N. Kornegay Street.
Nymirra J. Bynum, 23, of Goldsboro, was found dead inside a home.
Police said the suspect, Jaalin Dasani Applewhite, 21, also of Goldsboro, and Bynum were involved in a domestic altercation.
On Wednesday morning, Applewhite turned himself in, police said.
He was served on a warrant for murder and taken into custody.
Applewhite was being held at the Wayne County Detention Center under no bond.