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Robert Fox Jr., 17, of the 700 block of Magnolia Street in Sanford, was arrested and charged with first-degree murder Saturday.
On Friday, police announced that three suspects have been arrested in connection with the shooting that police described as drug-related:
Jontrell Orlando Wilson, 23, of the 3600 block of Renee Drive in Sanford, was arrested and charged with first-degree murder.
Shakur Antonio Sellers, 24, of the 2600 block of Mt. Pisgah Church Road in Sanford, was arrested and charged with first-degree murder.
Latavious Kwame McIver, 28, of the 500 block of Pineland Street in Sanford, was arrested and charged with first-degree murder.
All four suspects are being held in the Lee County Jail under no bond.
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They are all scheduled to appear in court Monday.
Sanford police respond to deadly shooting
The victim was identified as Dirk Anthony Lequia, 30, of Palmetto, Florida.